Comparison of Four Dental Pulp-Capping Agents by Cone-Beam Computed Tomography and Histological Techniques—A Split-Mouth Design Ex Vivo Study

Dental pulp-capping is done to preserve vital teeth when the pulp exposed due caries, trauma or instrumentation. Various materials are used as agents. The introduction of newer requires scientific studies assess their clinical efficacy. study was designed a split-mouth randomized analysis four agents (calcium hydroxide, mineral trioxide aggregate (MTA), Biodentine and EndoSequence root repair material (ERRM)). Based on selection criteria, 15 orthodontic patients requiring extraction premolars (60 total) were included in study. After pulp-capping, extracted after 8 weeks. We analyzed using cone-beam computed tomography (CBCT) histological sections determine quality dentinal bridge pulpal response. Ordinal scores given based completeness bridge, type degree inflammation. Results Kruskal–Wallis test (p < 0.05) with post hoc Conover values being applicable. All elicited formation (60/60). MTA had highest (10/15) followed by ERRM (8/15). Both showed more samples complete bridges (9/15 each) favorable response (15/15). Teeth capped calcium hydroxide cases incomplete (9/15) These differences inflammation statistically significant 0.001 p 0.00005, respectively), tests revealing no between 0.49 0.71, respectively). performed better than other but did not differ significantly from each other. individual preference for may be efficacy handling characteristics.